Endocrine Abstracts

Introduction: It is known that growth hormone secretion is affected by age and patient’s sex. We have assessed pre-treatment IGF-1 levels and responses to a standard dose of exogenous growth hormone (0.4 mg daily) in males and females arbitrarily categorised into young (20–40 yrs), middle-aged (40–60 yrs) and elderly (over 60 yrs). All patients were growth hormone deficient on either an insulin tolerance test or a glucagon test, peak growth hormone did not rise ...